Discussion on solving drug-resistant issues using antibody-based drugs

Abstract

As the problem of drug resistance increases, which dramatically threatens current therapies, all public health-related agencies are trying to find potential solutions to these issues. Most efforts are focused on the drugs themselves, searching for alternative substances with different actions and mechanisms to inhibit or kill resistant pathogens. However, it may be beneficial to approach the problem from a different perspective. Antibodies, a type of polypeptide usually produced during the adaptive immune response, have begun to show considerable potential in solving these problems. Currently, antibody-conjugate drugs have shown excellent results in the treatment of cancers and, in some cases, viral infections. Thus, the hypothesis has been proposed that using antibodies or antibody-based drugs could treat diseases such as common bacterial or viral infections. Therefore, this may provide alternative approaches for solving these problems.